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Amniocentesis Test And Chorionic Villus Sampling Test For Whom ?

What is Amniocentesis Test

In some cases when screening tests like Triple Marker and AFP (Alpha-Feto-Protein) are not normal or if there is a past history of child born with genetic defects (Down’s, thalessemia, sickle cell major, haemophilia, cystic fibrosis etc), there may be necessity to take out some fetal tissue for genetic testing such as amniocentesis or Chorionic Villus Sampling (CVS).

Amniocentesis Procedure

Amniocentesis procedure is done around 16 weeks of pregnancy, in some cases amniocentesis test may be done earlier or later.

Small amount of amniotic fluid is taken out from the pregnant mother’s abdomen under the guidance of an ultrasound with a needle passed into the uterine cavity. The amniotic fluid that contains fetal cells will be analyzed for the detection of abnormalities of the nervous system, Down’s syndrome, mental handicaps, or any inherited disorders.

Amniocentesis Risks

Though it is done under hygienic conditions, there is a chance of 1-2% that it might lead to a spontaneous abortion.

The couple should decide first what they are going to do with the results of the test. If the test shown any abnormality, are they really ready for the termination of the pregnancy? This is rather tough. Your doctor will be the right person to guide you about it and is mostly suggested for a woman who already has one abnormal child.

Chorionic Villus Sampling or CVS

This test is done in early pregnancy to determine some genetic disorders like Tay-Sach’s Disease, Down’s syndrome, Sickle Cell Anemia or Thalassemia.  This procedure also involves inserting a needle into the uterus cavity to suck out a very small bit of tissue. This procedure also involves a risk of damage to the fetal limb or an abortion.

Find below the other routine tests that are performed during pregnancy



DFMC (Daily Foetal Movement Count)



CVS or Chorionic Villus Sampling