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Fertility Drugs/medicines

Fertility drugs/ Medicines (for hormonal problems and/or to stimulate ovulation)

Medicines are mainly used to help with the ovulation. Ovulation is partially controlled by hormones called gonadotrophins (made in a gland just under the brain called pituitary gland). A gonadotrophin is a hormone which stimulates the activity of the gonads (ovaries in women and the testes in men). The main gonadotrophins that are made by the pituitary gland are called follicle-stimulating hormone (FSH) and luteinising hormone (LH), which pass into the bloodstream and travel to the ovaries.

The most common fertility drugs used to stimulate the ovulation are:

Clomid - Clomid is the first medication most doctors use in treating infertility in women that is taken orally. Research indicates that 40% of couples get pregnant using Clomid within six cycles. If this does not work even after taking for six menstrual cycles, your doctor may prescribe you other treatment options.
A woman takes Clomid on days 3 to 5 of her menstrual cycle.
It causes ovulation in 80% of women who are treated.
Clomid increases the risk of having a multiple pregnancy. There is a chance of twins up to 10% but triplets or more is less than 1%.

Gonadotropin and Human Chorionic Gonadotropin (hCG) - Gonadotropins are injected in women to make the eggs grow in the ovaries leading to ovulation. This is prescribed when a woman does not respond to Clomid. Gondotropin includes FSH or LH or a combination of both. These medications are also used during IVF procedures to stimulate follicle growth.

  • These are injected on day 2 or day 3 of a woman’s menstrual cycle for 7 to 12 days.
  • While treating a woman with gonadotropins, her doctor uses transvaginal ultrasound to monitor the size of her eggs.
  • Chances of a multiple births are higher with gonadotropins than Clomid. 30% of women who become pregnant with this drug have multiple births (about two-thirds are twins and the rest are triplets or more)
Bromocriptine or Cabergoline - Bromocriptine or cabergoline pills are taken orally to treat high levels of hormone prolactin, which stops ovulation to some drugs. Thyroid and kidney disease can cause high levels of prolactin.
  • These fertility drugs allow 90% of women to have normal prolactin levels.
  • 80% of women ovulate, once the prolactin levels come to normal range after using Bromocriptine or Cabergoline.

Articles you may be interested in:

Causes for male infertility

Causes for female infertility

Treatments for male infertility

Fertility treatment options for female

Possible complications of infertility treatments

Sperm banking

Surgical Treatment For Female Infertility

IUI (intrauterine Insemination)

In Vitro Fertilization (ivf)

Third Party Assistance (donors Sper, Donors Egg, Surrogacy)